MCCG

Discontinued Product

0712 has been discontinued.

View all Glutamate (Metabotropic) Group II Receptors products.
说明: Group II mGlu agonist/antagonist
化学名: (2S,3S,4S)-2-Methyl-2-(carboxycyclopropyl)glycine
说明书
引用文献
评论
文献 (4)

生物活性 for MCCG

Group II metabotropic glutamate receptor antagonist in electrophysiological studies and at cloned receptors. Group II mGlu agonist in adult rat cerebrocortical slices.

技术数据 for MCCG

分子量 173.17
储存 Store at RT
CAS Number 157381-42-5

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for MCCG

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参考文献 for MCCG

参考文献是支持产品生物活性的出版物。

Jane et al (1994) Actions of two new sub-type selective metabotropic glutamate receptor antagonists in the neonatal rat spinal cord. Br.J.Pharmacol. 112 809 PMID: 7921606

Kemp et al (1996) Agonists of cyclic AMP-coupled metabotropic glutamate receptors in adult rat cortical slices. Eur.J.Pharmacol. 309 79 PMID: 8864697

Knöpfel et al (1995) Pharmacological characterization of MCCG and MAP4 at the mGluR1b, mGluR2 and mGluR4a human metabotropic glutamate receptor subtypes. Neuropharmacology 34 1099 PMID: 8532159

Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745

关键词: MCCG, MCCG supplier, Glutamate, (Metabotropic), Group, II, Receptors, 0712, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。


Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.