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KI-7

Cat. No. 6787 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6787 has been discontinued.

View all Adenosine A<sub>2B</sub> Receptors products.
说明： Positive allosteric modulator of A2B receptors
化学名： α-Oxo-N-phenyl-1-(phenylmethyl)-1H-indole-3-acetamide
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for KI-7

KI-7 is an adenosine A2B receptor positive allosteric modulator. Potentiates the NECA (Cat. No. 1691) -induced increase in cAMP production in CHO cells expressing A2B receptors. Also potentiates the effects of NECA and the A2B receptor agonist BAY 60-6583 (Cat. No. 4472) in mediating osteoblast differentiation from MSCs in vitro.

化合物库 for KI-7

KI-7 is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Stem Cell Library. 了解 Tocris 化合物库的更多信息。

技术数据 for KI-7

分子量 354.4
公式 C23H18N2O2
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 1489263-00-4
PubChem ID 73350966
InChI Key MQMGZFRIEZRHHJ-UHFFFAOYSA-N
Smiles O=C(C(C1=CN(C2=CC=CC=C12)CC3=CC=CC=C3)=O)NC4=CC=CC=C4

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for KI-7

参考文献是支持产品生物活性的出版物。

Trincavelli et al (2014) Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. Biochim.Biophys.Acta 1843 2957 PMID: 25241343

Trincavelli et al (2014) Allosteric modulators of human A2B adenosine receptor. Biochim.Biophys.Acta 1840 1194 PMID: 24361612

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关键词: KI-7, KI-7 supplier, adenosine, A2B, receptor, positive, allosteric, modulators, PAMs, modulates, mesenchymal, stem, cells, MSCs, osteoblast, differentiation, Adenosine, Receptors, Mesenchymal, Stem, Cells, 6787, Tocris Bioscience

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