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说明： Caged Raseglurant (Cat. No. 4416)
化学名： (7-(Diethylamino)-2-oxo-2H-chromen-4-yl)methyl (2-((3-fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-yl)carbamate
纯度： ≥98% (HPLC)
生物活性 for JF-NP-26
JF-NP-26 is a caged Raseglurant (Cat. No. 4416). Releases raseglurant upon exposure to 405 nm (violet) light. Inhibits the effects of Quisqualate (Cat. No. 0188) in cultured neurons when exposed to 405 nm light. Exhibits analgesic activity in pain models in vivo on photoactivation. Quantum yield = 0.18.
技术数据 for JF-NP-26
| 分子量 | 513.56 |
| 公式 | C30H28FN3O4 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 2341841-03-8 |
| Smiles | CC1=CC(C)=C(NC(OCC2=CC(OC3=C2C=CC(N(CC)CC)=C3)=O)=O)C(C#CC4=CC=CC(F)=C4)=N1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for JF-NP-26
参考文献 for JF-NP-26
参考文献是支持产品生物活性的出版物。
Font et al (2017) Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. eLIFE 6 e23545 PMID: 28395733
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关键词: JF-NP-26, JF-NP-26 supplier, caged-raseglurant, ADX, 10059, photoactivation, photolysis, violet, light, mGlu5, receptors, NAM, negative, allosteric, modulator, Caged, Glutamate, Compounds, 6553, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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