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Submit ReviewIndorenate hydrochloride
说明： 5-HT1A, 5-HT1B and 5-HT2C agonist
别名： TR 3369
化学名： α-(Aminomethyl)-5-methoxy-1H-indole-3-acetic acid methyl ester hydrochloride
纯度： ≥98% (HPLC)
生物活性 for Indorenate hydrochloride
5-HT receptor agonist with high affinity for 5-HT1A receptors (pKd = 7.8) and lower affinity for 5-HT1B and 5-HT2C receptors (pKd values are 5.44 and 6.49 respectively). Possesses anti-hypertensive, anxiolytic and anorectic activity in vivo.
技术数据 for Indorenate hydrochloride
| 分子量 | 284.74 |
| 公式 | C13H16N2O3.HCl |
| 储存 | Desiccate at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 72318-55-9 |
| Smiles | NCC(C(OC)=O)C2=CNC1=CC=C(OC)C=C12.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Indorenate hydrochloride
参考文献 for Indorenate hydrochloride
参考文献是支持产品生物活性的出版物。
Velazquez-Martinez et al (1999) Discriminative stimulus properties of indorenate, a serotonin agonist. J.Psychiatry Neurosci. 24 122 PMID: 10212554
Sanchez and Velazquez-Martinez (2001) Discriminative stimulus properties of indorenate, a 5-HT1A, 5-HT1B and 5-HT2C agonist: a study in rats. J.Psychopharmacol. 15 29 PMID: 11277605
Miranda et al (2003) Further evidence that the discriminative stimulus properties of indorenate are mediated by 5-HT1A/1B/2C receptors. Pharmacol.Biochem.Behav. 74 371 PMID: 12479957
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关键词: Indorenate hydrochloride, Indorenate hydrochloride supplier, 5-HT1A, 5-HT1B, 5-HT2C, agonists, Serotonin, Receptors, TR3369, TR, 3369, 2399, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
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