DMNPE-4 AM-caged-calcium

Name: DMNPE-4 AM-caged-calcium
Brand: Tocris Bioscience
SKU: 5948

Cat. No. 5948 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5948 has been discontinued.

View all Caged Second Messenger Compounds products.

说明： Calcium cage; cell permeable

化学名： Bis(acetoxymethyl) 3,12-bis(2-(acetoxymethoxy)-2-oxoethyl)-5-(4,5-dimethoxy-2-nitrophenyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioate

纯度： ≥90% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for DMNPE-4 AM-caged-calcium

DMNPE-4 AM-caged-calcium is a calcium cage. In the presence of calcium, the compound will chelate and cage calcium (K_d values are 48 and 19 nM at pH 7.2 and 7.4, respectively; K_d after uncaging = 2 mM). DMNPE-4 AM-caged-calcium is selective for Ca²⁺ over Mg²⁺ (K_d = 10 mM). Rapid and efficient calcium release occurs upon photolysis at 350 nm. It can also be used for two-photon uncaging. Extinction coefficient of 5120 M^-1 cm^-1, quantum yield 0.09. Cell permeable.

技术数据 for DMNPE-4 AM-caged-calcium

分子量	849.74
公式	C₃₄H₄₇N₃O₂₂
储存	Store at -20°C
纯度	≥90% (HPLC)
CAS Number	2253744-58-8
PubChem ID	137919855
InChI Key	UUZFENOXYOBVDU-UHFFFAOYSA-N
Smiles	O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)CCOCCOC(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(C=C1OC)=C(C=C1OC)[N+]([O-])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for DMNPE-4 AM-caged-calcium

分析证书/产品说明书

化学品安全技术说明书

参考文献 for DMNPE-4 AM-caged-calcium

参考文献是支持产品生物活性的出版物。

Wang et al (2015) Spontaneous activity of cochlear hair cells triggered by fluid secretion mechanism in adjacent support cells Cell 163 1348 PMID: 26627734

Gordon et al (2008) Brain metabolism dictates the polarity of astrocyte control over arterioles. Nature 456 745 PMID: 18971930

Ellis-Davies et al (2006) Tuning caged calcium: photolabile analogues of EGTA with improved optical and chelation properties. Cell Calcium 39 75 PMID: 16303177

按标靶查看相关产品

关键词: DMNPE-4 AM-caged-calcium, DMNPE-4 AM-caged-calcium supplier, Caged, calcium, cell, permeable, rapid, photolysis, Second, Messenger, Compounds, Ca2+-Activated, Chloride, Channels, Non-selective, Cav, Potassium, General, Calcium, Signaling, Agents, 5948, Tocris Bioscience

篇 DMNPE-4 AM-caged-calcium 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 DMNPE-4 AM-caged-calcium 的引用文献。