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Cys-T7 Peptide

Cat. No. 8904 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Targeting peptide for the transferrin receptor (N-term Cys)
纯度： ≥95% (HPLC)
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引用文献
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生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Cys-T7 Peptide

Cys-T7 Peptide is a targeting peptide for the transferrin receptor (N-term Cys), a protein abundantly expressed on endothelial cells, including those forming the blood-brain barrier (BBB). Cys-T7 Peptide facilitates receptor-mediated endocytosis and transcytosis, making it an ideal targeting agent for drug delivery systems, such as lipid nanoparticles (LNPs), across biological barriers. N-term cys residue enables thiol-maleimide-based conjugation to DSPE-PEG 2000 Maleimide (Cat. No. 7947) commonly used to synthesize LNPs.

技术数据 for Cys-T7 Peptide

分子量 996.15
公式 C44H65N15O10S
序列 CHAIYPRH
储存 Store at -20°C
纯度 ≥95% (HPLC)
InChI Key SMAWGRDHSYDHOY-WBLMYSKVSA-N
Smiles O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CC=C(C=C2)O)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CNC=N4)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Cys-T7 Peptide

溶解性 Soluble to 2 mg/ml in water

参考文献 for Cys-T7 Peptide

参考文献是支持产品生物活性的出版物。

Han et al (2011) Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer. Biomaterials 32 1242 PMID: 20971503

Han et al (2025) Peptide-functionalized lipid nanoparticles for targeted systemic mRNA delivery to the brain. Nano Lett. 25 800 PMID: 39688915

If you know of a relevant reference for Cys-T7 Peptide, please let us know.

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关键词: Cys-T7 Peptide, Cys-T7 Peptide supplier, Lipid, nanoparticles, LNP, mRNA, peptides, brain, delivery, blood-brain, barrier, neurons, endocytosis, transcytosis, Nanoparticles, Biochemicals, and, Molecular, Biology, Endocytosis, 8904, Tocris Bioscience

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