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View all Glutamate (Metabotropic) Group II Receptors products.One of the isomers of (±)-cis-ACPD. Similar action at mGlu receptors to (1S,3R)-ACPD, but more selective for group II. Little or no NMDA receptor agonist activity.
分子量 | 173.17 |
储存 | Store at RT |
CAS Number | 111900-31-3 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Holscher et al (1997) Block of theta-burst-induced long-term potentiation by (1S,3S)-1,3-dicarboxylic acid: further evidence against long-term potentiation as a model for learning. Neuroscience 81 17 PMID: 9300397
Jane et al (1991) Action of two new antagonists showing selectivity for different sub-types of metabotropic glutamate receptor in the neonatal rat spinal cord. Br.J.Pharmacol. 112 809 PMID: 7921606
Pin and Duvoisin (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34 26 PMID: 7623957
Watkins and Collingridge (1994) Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. TiPS 15 333 PMID: 7992387
关键词: (1S,3S)-ACPD, (1S,3S)-ACPD supplier, Glutamate, (Metabotropic), Group, II, Receptors, 0300, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.