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Submit ReviewUNC 2399
说明： Biotinylated UNC 1999 (Cat.No. 4904)
化学名： 1-Isopropyl-N-[(6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl]-6-[6-[4-[41-oxo-45-[(3aS,4aS,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10,13,16,19,22,25,28,31,34,37-dodecaoxa-40-azapentatetracontan-1oyl]piperazin-1-yl]pyridin-3-yl]-1H-indazole-4-carboxamide
纯度： ≥95% (HPLC)
生物活性 for UNC 2399
UNC 2399 is a biotinylated UNC 1999 (Cat.No. 4904, IC50 = 17 nM). Enriches lysine methyltransferase EZH2 from HEK293T cells.
Negative control also avilable.
许可信息
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the UNC 1999 probe summary on the SGC website.
技术数据 for UNC 2399
| 分子量 | 1353.66 |
| 公式 | C67H104N10O17S |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 2412791-72-9 |
| PubChem ID | 118732748 |
| InChI Key | PSDIDGKZEPMSHC-FRQYIUQJSA-N |
| Smiles | CC(C)N(N=C1)C2=C1C(C(NCC3=C(CCC)C=C(C)NC3=O)=O)=CC(C(C=C4)=CN=C4N5CCN(C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC[C@H]6[C@]([H])([C@]([H])(CS6)N7)NC7=O)=O)=O)CC5)=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for UNC 2399
参考文献 for UNC 2399
参考文献是支持产品生物活性的出版物。
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关键词: UNC 2399, UNC 2399 supplier, UNC2399, biotinylated, biotin, tag, EZH2, EZH1, histone, methyltransferase, inhibitors, inhibits, UNC1999, pull, down, PRC2, polycomb, repressive, complex, 2, Lysine, Methyltransferases, 4930, Tocris Bioscience
1 篇 UNC 2399 的引用文献
引用文献是使用了 Tocris 产品的出版物。 UNC 2399 的部分引用包括：
Konze et al (2013) An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1. ACS.Chem.Biol. 8 1324 PMID: 23614352
UNC 2399 的评论
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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