(R)-Citalopram oxalate

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Cat.No. 5763 - (R)-Citalopram oxalate | C20H21FN2O.C2H2O4 | CAS No. 219861-53-7
说明: Enantiomer of escitalopram oxalate (Cat. No. 1427)
化学名: (-)-(R)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
纯度: ≥98% (HPLC)
说明书
引用文献
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文献 (2)

生物活性 for (R)-Citalopram oxalate

(R)-Citalopram oxalate is an enantiomer of escitalopram oxalate. Postulated to allosterically modulate the affinity of the S-enantiomer.

Racemate and S-enantiomer also available.

技术数据 for (R)-Citalopram oxalate

分子量 414.43
公式 C20H21FN2O.C2H2O4
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 219861-53-7
PubChem ID 45038690
InChI Key KTGRHKOEFSJQNS-VEIFNGETSA-N
Smiles FC(C=C3)=CC=C3[C@@]1(CCCN(C)C)OCC2=C1C=CC(C#N)=C2.OC(C(O)=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for (R)-Citalopram oxalate

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 20.72 50
DMSO 41.44 100

制备储备液 for (R)-Citalopram oxalate

以下数据基于产品分子量 414.43。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.41 mL 12.06 mL 24.13 mL
5 mM 0.48 mL 2.41 mL 4.83 mL
10 mM 0.24 mL 1.21 mL 2.41 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

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产品说明书 for (R)-Citalopram oxalate

参考文献 for (R)-Citalopram oxalate

参考文献是支持产品生物活性的出版物。

Jacquot et al (2007) Escitalopram and citalopram: the unexpected role of the R-enantiomer. Encephale 33 179 PMID: 17675913

Sánchez et al (2006) The pharmacology of cital. enantiomers: the antagonism by R-citalopram on the effect of S-citalopram. Basic & Clinical Pharmacology & Toxicology 99 91 PMID: 16918708


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关键词: (R)-Citalopram oxalate, (R)-Citalopram oxalate supplier, Enantiomers, escitalopram, oxalate, 5-HT, reuptake, modulators, allosteric, SERT, 5-hydroxytryptamine, monoamine, neurotransmitters, citalopram, depression, Transporters, 5763, Tocris Bioscience

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