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Submit ReviewG418 disulfate salt
说明： Aminoglycoside antibiotic; used in cell culture
生物活性 for G418 disulfate salt
G418 disulfate salt is an aminoglycosidic antibiotic. Inhibits protein synthesis in both prokaryotic and eukaryotic cells. Used for selection of eukaryotic cells transfected with the neo gene.
This product has been cell culture tested.
技术数据 for G418 disulfate salt
| 分子量 | 692.71 |
| 公式 | C20H40N4O10.2H2SO4 |
| 储存 | Store at +4°C |
| CAS Number | 108321-42-2 |
| PubChem ID | 206347 |
| InChI Key | UHEPSJJJMTWUCP-DHDYTCSHSA-N |
| Smiles | N[C@H]1[C@H](O[C@]2([H])[C@H](O)[C@@H](NC)[C@@](C)(O)CO2)[C@@H](O)[C@H](O[C@]3([H])[C@H](N)[C@@H](O)[C@H](O)[C@]([C@H](O)C)([H])O3)[C@@H](N)C1.OS(O)(=O)=O.OS(O)(=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for G418 disulfate salt
参考文献 for G418 disulfate salt
参考文献是支持产品生物活性的出版物。
Wagman et al (1974) Antibiotic G-418, a new Micromonospora-produced aminoglycoside with activity against protozoa and helminths: fermentation, isolation and preliminary characterization. Antimicrob.Agents Chemother. 6 144 PMID: 15828184
Bar-Nun et al (1983) G-418, an elongation inhibitor of 80 S ribosomes. Biochim.Biophys.Acta. 741 123 PMID: 6193810
Burke and Mogg (1985) Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromo. Nucleic Acids Res. 13 6265 PMID: 2995924
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关键词: G418 disulfate salt, G418 disulfate salt supplier, antibiotics, neomycin, resistance, cell, culture, aminoglycoside, inhibitors, inhibits, protein, synthesis, eukaryotes, eukaryotic, prokaryotes, prokaryotic, DNA,, RNA, and, Protein, Synthesis, Antibiotics, 4131, Tocris Bioscience
1 篇 G418 disulfate salt 的引用文献
引用文献是使用了 Tocris 产品的出版物。 G418 disulfate salt 的部分引用包括：
Yuan-Soon et al (2021) Curcumin-induced antitumor effects on triple-negative breast cancer patient-derived xenograft tumor mice through inhibiting salt-induced kinase-3 protein. J Food Drug Anal 29 622-637 PMID: 35649138
G418 disulfate salt 的评论
平均评分: 4 (Based on 1 Review.)
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G418 maintains stable expression of recombinant hRyR2 in HEK293 cells..
By
Niroj Shrestha on 01/26/2019
分析类型： In Vitro
种属： Human
细胞系/组织： HEK293
G418 was reconstituted in milli-Q water to get a stock solution of 50 mg/ml. The stock was diluted to 250 mcg/ml in DMEM containing 10% FBS, 4 mM glutamine, 10 mM HEPES and puromycin (5 mcg/ml) and used to culture HEK293 cell line, stably expressing hRyR2-IRES-GFP.
Stock solutions should be stored in aliquots at -20°C.
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Cell Cycle and DNA Damage Research Product Guide
This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:
- Cell Cycle and Mitosis
- DNA Damage Repair
- Targeted Protein Degradation
- Ubiquitin Proteasome Pathway
- Chemotherapy Targets
Huntington's Disease Research Product Guide
This product guide provides a background to Huntington's disease research and lists around 100 products for the study of:
- Somatic Instability
- Proteolysis and Inclusion Bodies
- Transcriptional Dysregulation
- Mitochondrial Dysfunction
- Nuclear-Cytoplasmic Transport Interference
- Excitotoxicity
- Stem Cells