BIM, Biotinylated

Discontinued Product

3526 has been discontinued.

View all Bcl-2 Family products.
说明: Bim peptide fragment
说明书
引用文献
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文献 (2)
通路 (1)

生物活性 for BIM, Biotinylated

BIM, Biotinylated is a bim peptide fragment (residues 81-106) with a biotin moiety attached.

技术数据 for BIM, Biotinylated

分子量 3637.14
公式 C161H247N49O44S2
序列 AADMRPEIWIAQELRRIGDEFNAYYARR

(Modifications: Ala-1 = (Biotin)-β-Ala, Ala-2 = β-Ala, Arg-28 = C-terminal amide)

储存 Store at -20°C
PubChem ID 90488855
InChI Key PSNCGLAAPGGYMJ-YLKYZDBHSA-N
Smiles [H]N(CCC(=O)NCCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C(=O)CCCC[C@@H]1SC[C@]2([H])NC(=O)N[C@]12[H]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for BIM, Biotinylated

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参考文献 for BIM, Biotinylated

参考文献是支持产品生物活性的出版物。

Whitfield et al (2003) High-throughput methods to detect dimerization of Bcl-2 family proteins. Anal.Biochem. 322 170 PMID: 14596824

Wang et al (2006) Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins. J.Med.Chem. 49 6139 PMID: 17034116

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关键词: BIM, Biotinylated, BIM, Biotinylated supplier, Bim, peptide, fragment, Bcl-2, Family, 3526, Tocris Bioscience

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