You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
VH 032 amide-alkylC4-amine
生物活性 for VH 032 amide-alkylC4-amine
VH 032 amide-alkylC4-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.
This product has been recently renamed. The previous name for this product was VH 032 - linker 3
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines for VH 032 amide-alkylC4-amine
This product is provided for use in onward chemistry. Suitable solvents can be used.
技术数据 for VH 032 amide-alkylC4-amine
|储存||Store at -20°C|
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献 for VH 032 amide-alkylC4-amine
Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID: 28302825
If you know of a relevant reference for VH 032 amide-alkylC4-amine, please let us know.
关键词: VH 032 amide-alkylC4-amine, VH 032 amide-alkylC4-amine supplier, Proteolysis, Targeting, Chimera, PROTACs, von-Hippel-Lindau, protein, ligand, VHL, E3, ubiquitin, ligase, short, alkyl, linker, conjugate, VH032, 2245697-83-8, 2341796-78-7, VH, 032, -, 3, Ligands, Plus, Linkers, 6465, Tocris Bioscience
篇 VH 032 amide-alkylC4-amine 的引用文献
引用文献是使用了 Tocris 产品的出版物。
目前没有 VH 032 amide-alkylC4-amine 的引用文献。 您是否知道使用了 Tocris VH 032 amide-alkylC4-amine 的优秀论文？ 请告知我们.
VH 032 amide-alkylC4-amine 的评论
平均评分: 5 (Based on 1 Review.)
Have you used VH 032 amide-alkylC4-amine?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
to make PROTACS
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
Targeted Protein Degradation Poster
Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia