Tocriscreen FDA-Approved Drugs Library

Discontinued Product

7200 has been discontinued.

View all Tocriscreen™ Compound Libraries products.
说明: Drug repurposing library; a library of 190 compounds equivalent to active components of drug formulations approved by the FDA (100 μL 10 mM DMSO solutions)
说明书
引用文献 (7)
评论

生物活性 for Tocriscreen FDA-Approved Drugs Library

Tocriscreen FDA-Approved Drugs Library is a library of 190 compounds equivalent to the pharmacologically active components of drug formulations approved by the FDA. Compounds supplied pre-dissolved in DMSO (100 μL, 10 mM solution). Contains compounds covering a diverse range of pharmaceutical targets and therapeutic areas e.g. immunology, oncology. Includes both established therapeutics, e.g. tamoxifen (Cat. No. 0999) and paclitaxel (Cat. No. 1097), as well as more recently approved drugs such as darunavir (Cat. No. 6710) and sorafenib (Cat. No. 6814). Ideal for in vitro and in vivo drug repurposing/repositioning studies.

This library replaces the Tocriscreen Library of FDA-Approved Compounds (Cat. No. 5932).

All Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

Key Format and Product Details for Tocriscreen FDA-Approved Drugs Library

  • All compounds are equivalent to active components of FDA-approved drug formulations
  • Full chemical and biological data available in Excell and SD file formats
  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Compounds arranged with a maximum of 80 per rack with 3 racks per library
  • Pre-dissolved in 100 μL 10 mM DMSO solutions
  • Compounds produced to same high chemical standard as Tocris catalog
Target Classes Covered by the Tocriscreen FDA-approved Drugs Library

The Tocriscreen FDA-approved Drugs Library contains bioactive compounds covering a diverse range of therapeutic classifications, derived using the WHO Anatomical Therapeutic Chemical Classification System code (ATC code).

技术数据 for Tocriscreen FDA-Approved Drugs Library

储存 Store at -20°C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Tocriscreen FDA-Approved Drugs Library

分析证书目前不在网上提供。
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参考文献 for Tocriscreen FDA-Approved Drugs Library

参考文献是支持产品生物活性的出版物。

Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17 195 PMID: 26253201

Edwards et al (2014) The University of New Mexico Center for Molecular Discovery. Comb.Chem.High Throughput Screen. 17 256 PMID: 24409953

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关键词: Tocriscreen FDA-Approved Drugs Library, Tocriscreen FDA-Approved Drugs Library supplier, biologically, active, pre-dissolved, DMSO, 10mM, solutions, Tocriscreen, Compound, Collections, Screening, Library, Libraries, HTS, HCS, high, throughput, content, FDA-approved, drug, library, repurposing, target, validation, repositioning, 7200, Tocris Bioscience

7 篇 Tocriscreen FDA-Approved Drugs Library 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Tocriscreen FDA-Approved Drugs Library 的部分引用包括:

Shin et al (2018) Saracatinib Inhibits Middle East Respiratory Syndrome-Coronavirus Replication In Vitro. Viruses 10 E283 PMID: 29795047

Edmister et al (2022) Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles. Sci.Rep. 12 6120 PMID: 35449173

Chaffey et al (2024) Drug repurposing screen identifies novel anti-inflammatory activity of sunitinib in macrophages. Eur.J.Pharmacol. 969 176437 PMID: 38417608

Kim et al (2023) Nebivolol sensitizes BT-474 breast cancer cells to FGFR inhibitors. Anticancer Res. 43 1973 PMID: 37097659


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