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Submit ReviewPemoline
说明： CNS stimulant, indirect monoamine agonist
别名： Phenoxazole,Phenylisohydantoin
化学名： 2-Amino-5-phenyl-4(5H)-oxazolone
纯度： ≥99% (HPLC)
生物活性 for Pemoline
Long-acting central stimulant that induces self-injurious behavior in rats. Acts as an indirect monoamine agonist.
技术数据 for Pemoline
| 分子量 | 176.17 |
| 公式 | C9H8N2O2 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 2152-34-3 |
| PubChem ID | 4723 |
| InChI Key | NRNCYVBFPDDJNE-UHFFFAOYSA-N |
| Smiles | O=C1C(C2=CC=CC=C2)OC(N)=N1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Pemoline
参考文献 for Pemoline
参考文献是支持产品生物活性的出版物。
Mueller and Nyhan (1982) Pharmacologic control of pem. induced self-injurious behavior in rats. Pharmacol.Biochem.Behav. 16 957 PMID: 6213967
Kies and Devine (2004) Self-injurious behaviour: a comparison of caffeine and pem. models in rats. Pharmacol.Biochem.Behav. 79 587 PMID: 15582667
Muehlmann et al (2008) Pemoline (2-Amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy. J.Pharmacol.Exp.Ther. 324 214 PMID: 17925479
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关键词: Pemoline, Pemoline supplier, CNS, stimulant, indirect, monoamine, agonists, Dopaminergic, Dopamine, Receptors, Adrenergic, Compounds, Adrenoceptors, Serotonin, 5-HT-, 5-Hydroxytryptamine, Phenoxazole, Phenylisohydantoin, Dopaminergic-Related, Related, 5-HT-Related, 5-HT3, 3045, Tocris Bioscience
1 篇 Pemoline 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Pemoline 的部分引用包括：
Jones et al (2015) Manipulating circadian clock neuron firing rate resets molecular circadian rhythms and behavior. Nat Neurosci 18 373 PMID: 25643294
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.