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Submit ReviewA potent antagonist at NK1 receptors.
分子量 | 588.71 |
公式 | C36H36N4O4 |
储存 | Store at RT |
CAS Number | 138449-07-7 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Fujii et al (1992) Pharmacological profile of a high affinity dipeptide NK1 receptor antagonist. FK888. Br.J.Pharmacol. 107 785 PMID: 1282073
Goso et al (1994) Comparison of tachykinin NK1 receptors in human IM9 and U373MG cells, using antagonist (FK 888, (±)-CP-96,345 and RP67580) binding. Eur.J.Pharmacol. 254 221 PMID: 7516885
Wang et al (1994) Investigation of the specificity of FK 888 as a tachykinin NK1 receptor antagonist. Br.J.Pharmacol. 111 1342 PMID: 7518299
关键词: FK 888, FK 888 supplier, selective, NK1, receptors, antagonists, tachykinins, neurokinins, Receptor, 0696, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
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