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DBIA

Cat. No. 8142 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Chemoproteomic reagent, binds with reactive cysteines and labels with desthiobiotin
化学名： (4R,5S)-N-[2-[(2-Iodoacetyl)amino]ethyl]-5-methyl-2-oxo-4-imidazolidinehexanamide
纯度： ≥95% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for DBIA

DBIA (desthiobiotin iodoacetamide) is a chemoproteomic reagent. DBIA is a cysteine reactive probe used to label and purify proteins by attaching desthiobiotin to cysteine residues in the protein of interest. DBIA can be used for targeted protein labeling and purification studies.

技术数据 for DBIA

分子量 424.28
公式 C14H25IN4O3
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2924824-04-2
PubChem ID 166642567
InChI Key ASKKBTGJVCEXOA-WDEREUQCSA-N
Smiles ICC(NCCNC(CCCCC[C@@H]1[C@@H](NC(N1)=O)C)=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for DBIA

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 42.43 100

制备储备液 for DBIA

以下数据基于产品分子量 424.28。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.36 mL 11.78 mL 23.57 mL
5 mM 0.47 mL 2.36 mL 4.71 mL
10 mM 0.24 mL 1.18 mL 2.36 mL
50 mM 0.05 mL 0.24 mL 0.47 mL

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参考文献 for DBIA

参考文献是支持产品生物活性的出版物。

Kuljanin et al (2021) Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat.Biotechnol. 39 630 PMID: 33398154

If you know of a relevant reference for DBIA, please let us know.

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关键词: DBIA, DBIA supplier, chemoproteomic, reagents, cysteine, reactive, probe, cysteines, desthiobiotin, iodoacetamide, targeted, protein, labeling, proteins, purification, Biochemicals, and, Molecular, Biology, 8142, Tocris Bioscience

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