Corynanthine hydrochloride

Discontinued Product

1143 has been discontinued.

View all Adrenergic &alpha;<sub>1</sub> Receptors products.
说明: α1 antagonist
化学名: (16b,17a)-17-Hydroxy-yohimban-16-carboxylic acid methyl ester hydrochloride
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生物活性 for Corynanthine hydrochloride

α1-adrenoceptor selective antagonist.

技术数据 for Corynanthine hydrochloride

分子量 390.91
公式 C21H26N2O3.HCl
储存 Desiccate at +4°C
CAS Number 66634-44-4
Smiles COC(C1C2C(CCC1O)CN1CCc3c4ccccc4[nH]c3C1C2)=O.Cl

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Tocris products are intended for laboratory research use only, unless stated otherwise.

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参考文献 for Corynanthine hydrochloride

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Doxey et al (1984) Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine. Naunyn Schmiedebergs Arch.Pharmacol. 325 136 PMID: 6144048

Hertting and Jackisch (1985) Endogenous noradrenaline as modulator of hippocampal serotonin (5-HT)-release. Dual effects of yohimbine, rauwolscine and corynanthine as alpha-adrenoceptor antagonists and 5-HT receptor agonists. Naunyn Schmiedebergs Arch.Pharmacol. 329 216 PMID: 2991775

Sheppard et al (1981) Pre- and postsynaptic alpha adrenoceptor selectivity studies with yohimbine and its two diastereoisomers rauwolscine and corynanthine in the anesthetized dog. J.Pharmacol.Exp.Ther. 219 540 PMID: 6270312

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关键词: Corynanthine hydrochloride, Corynanthine hydrochloride supplier, Adrenergic, Alpha-1, Receptors, 1143, Tocris Bioscience

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Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.