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Submit ReviewStrontium chloride is a calcium sensing receptor (CaSR) agonist. Activates ERK1/2 signaling, intracellular calcium mobilization, and calcitonin secretion. Enhances osteogenic differentiation of mesenchymal stem cells.
分子量 | 158.53 |
公式 | SrCl2 |
储存 | Desiccate at RT |
CAS Number | 10476-85-4 |
PubChem ID | 61520 |
InChI Key | AHBGXTDRMVNFER-UHFFFAOYSA-L |
Smiles | Cl[Sr]Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Thomsen et al (2012) Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells. J.Pharmacol.Exp.Ther. 343 638 PMID: 22942242
Yang et al (2011) Strontium enhances osteogenic differentiation of mesenchymal stem cells and in vivo bone formation by activating Wnt/catenin signaling. Stem Cells 29 981 PMID: 21563277
关键词: Strontium chloride, Strontium chloride supplier, calcium, sensing, receptor, CaSR, agonists, ERK1/2, calcitonin, secretion, osteogenic, differentiation, stem, cells, Calcium-Sensing, Receptor, Mesenchymal, Stem, Cells, Osteogenic, 4749, Tocris Bioscience
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