Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewSNAP 398299
说明： Potent and selective GAL3 antagonist
化学名： 1,3-Dihydro-1-[3-[2-(1-pyrrolidinyl)ethoxy]phenyl]-3-[[3-(trifluoromethyl)phenyl]imino]-2H-indol-2-one
纯度： ≥97% (HPLC)
生物活性 for SNAP 398299
Potent and selective GAL3 antagonist (Ki = 5 nM). Exhibits greater than 100-fold selectively for GAL3 over GAL1, GAL2, adrenergic α1a and dopamine D5 receptors. Anxiolytic- and antidepressant-like effects in vivo.
技术数据 for SNAP 398299
| 分子量 | 479.49 |
| 公式 | C27H24F3N3O2 |
| 储存 | Store at -20°C |
| 纯度 | ≥97% (HPLC) |
| CAS Number | 903878-06-8 |
| PubChem ID | 11698643 |
| InChI Key | HXCJZIBJTFITNI-UHFFFAOYSA-N |
| Smiles | O=C3/C(C2=CC=CC=C2N3C4=CC(OCCN5CCCC5)=CC=C4)=N/C1=CC=CC(C(F)(F)F)=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for SNAP 398299
参考文献 for SNAP 398299
参考文献是支持产品生物活性的出版物。
Swanson et al (2005) Anxiolytic- and antidepressant-like profiles of the galanin-3 (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc.Natl.Acad.Sci.U.S.A 102 17489 PMID: 16287967
Konkel et al (2006) Amino substituted analogs of 1-phenyl-3-phenylimino-2-indolones with potent galanin Gal3 receptor binding affinity and improved solubility. Bioorg.Med.Chem.Lett. 16 3950 PMID: 16730981
按标靶查看相关产品
按产品操作查看相关产品
关键词: SNAP 398299, SNAP 398299 supplier, SNAP398299, high, affinity, selective, gal3, antagonists, antagonism, galanin, Galanin, Receptors, 5426, Tocris Bioscience
SNAP 398299 的评论
目前没有该产品的评论。 Be the first to review SNAP 398299 and earn rewards!
Have you used SNAP 398299?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.