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Submit Review(R)-(+)-m-Nitrobiphenyline oxalate
Discontinued Product
2948 has been discontinued.
View all Adrenergic α<sub>2</sub> Receptors products.
说明： Potent α2C agonist
化学名： (R)-2-[1-(3'-Nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole oxalate
纯度： ≥99% (HPLC)
生物活性 for (R)-(+)-m-Nitrobiphenyline oxalate
α2C-adrenoceptor agonist that potently inhibits cAMP accumulation in CHO cells (EC50 = 38 nM). Behaves as an antagonist at α2A and α2B adrenoceptors (pKb values are 7.11 and 6.07 respectively).
技术数据 for (R)-(+)-m-Nitrobiphenyline oxalate
| 分子量 | 401.38 |
| 公式 | C17H17N3O3.C2H2O4 |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 945618-97-3 |
| Smiles | O=C(O)C(O)=O.[H][C@](C3=NCCN3)(C)OC1=CC=CC=C1C2=CC([N+]([O-])=O)=CC=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for (R)-(+)-m-Nitrobiphenyline oxalate
参考文献 for (R)-(+)-m-Nitrobiphenyline oxalate
参考文献是支持产品生物活性的出版物。
Crassous et al (2007) α2-adrenoreceptor profile modulation. 3. 1 -(+)-m-Nitrobiphenyline, a new efficient α2C-subtype selective agonist. J.Med.Chem. 50 3964 PMID: 17630725
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关键词: (R)-(+)-m-Nitrobiphenyline oxalate, (R)-(+)-m-Nitrobiphenyline oxalate supplier, Potent, α2C-adrenoceptor, alpha2C-adrenoceptors, a2c-adrenoceptors, a2c-adrenergic, α2c-adrenergic, alpha2c-adrenergic, agonists, Receptors, Adrenergic, Alpha-2, 2948, Tocris Bioscience
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Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.