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PIR 3.5

Cat. No. 4212 3 篇引用文献 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4212 has been discontinued.

View all P21-activated Kinases products.
说明： Negative control of IPA 3 (Cat. No. 3622)
化学名： 6,6'-Dithiodi-2-naphthtol
纯度： ≥98% (HPLC)
说明书
引用文献 (3)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for PIR 3.5

PIR 3.5 is a negative control of IPA 3, a direct, non-competitive inhibitor of group I p21-activated kinase (Pak1).

Active Analog also available.

技术数据 for PIR 3.5

分子量 350.45
公式 C20H14O2S2
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 6088-51-3
PubChem ID 22463
InChI Key AHXGXXJEEHFHDK-UHFFFAOYSA-N
Smiles OC1=CC=C2C(C=CC(SSC3=CC(C=CC(O)=C4)=C4C=C3)=C2)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for PIR 3.5

参考文献是支持产品生物活性的出版物。

Deacon et al (2008) An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem.Biol. 15 322 PMID: 18420139

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关键词: PIR 3.5, PIR 3.5 supplier, PIR, 3.5, PIR3.5, negative, control, IPA-3, inhibits, Pak1, inhibitors, P21-activated, Kinases, 4212, Tocris Bioscience

3 篇 PIR 3.5 的引用文献

引用文献是使用了 Tocris 产品的出版物。 PIR 3.5 的部分引用包括：

Molosh et al (2014) Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase. J Biol Chem 17 1583 PMID: 25242307

Das et al (2017) Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala. Sci Rep 7 13930 PMID: 29066727

Imle et al (2015) Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex. MBio 6 PMID: 26350970

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