Okadaic acid ammonium salt 最新

Cat. No. 9012 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Protein phosphatase 1 and 2A inhibitor

化学名： 9,10-Deepithio-9,10-didehydroacanthifolicin ammonium salt

纯度： ≥98% (HPLC)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Okadaic acid ammonium salt

Okadaic acid ammonium salt is a potent inhibitor of protein phosphatase 1 (IC₅₀ = 3 nM) and protein phosphatase 2A (IC₅₀ = 0.2-1 nM). Displays > 100,000,000-fold selectivity over PP2B and PP2C. Tumor promoter. Shown to activate atypical protein kinase C in adipocytes.

技术数据 for Okadaic acid ammonium salt

分子量	822.04
公式	C₄₄H₆₇O₁₃.NH₄
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	175522-42-6
PubChem ID	162640608
InChI Key	ZBOMSHVRJSJGNR-GHIYGBLASA-N
Smiles	C[C@H]([C@H]1O[C@]2(OCCCC2)CC[C@H]1C)C[C@H](O)[C@@](C([C@H]3O)=C)([H])O[C@@](CC4)([H])[C@@]3([H])O[C@@]54CC[C@H](/C=C/[C@@H](C)[C@H](CC(C)=C6)O[C@@]76O[C@H](C[C@](O)(C)C([O-])=O)CC[C@H]7O)O5.[NH4+]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Okadaic acid ammonium salt

溶解性	Soluble in DMSO

产品说明书 for Okadaic acid ammonium salt

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Okadaic acid ammonium salt

参考文献是支持产品生物活性的出版物。

Cohen et al (1990) Okadaic acid: a new probe for the study of cellular regulation. TiBS 15 98 PMID: 2158158

Haystead et al (1989) Effects of the tumour promotor okadaic acid on intracellular protein phosphorylation and metabolism. Nature 337 78 PMID: 2562908

McCluskey et al (2002) Serine-threonine protein phosphatase inhibitors: development of therapeutic strategies. J.Med.Chem 45 1151 PMID: 11881984

Nuydens et al (1998) Okadaic acid-induced apopstosis in neuronal cells: evidence for an abortive mitotic attempt. J.Neurochem. 70 1124 PMID: 9489733

Deng et al (2023) Molecular dynamic simulation on the synergistic corrosion inhibition effect and mechanism of quinoline quaternary ammonium salt and L-methionine. Chem.Technol.Fuels.Oils 59 858

If you know of a relevant reference for Okadaic acid ammonium salt, please let us know.

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关键词: Okadaic acid ammonium salt, Okadaic acid ammonium salt supplier, [78111-17-8], Protein, phosphatase, 1, 2A, inhibitors, inhibits, Calcineurin, Ser/Thr, Phosphatases, PP1, PP2A, Okadaic, Acid, 9012, Tocris Bioscience

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