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Submit ReviewMammalian bombesin-like neuropeptide; first isolated from pig spinal cord. Stimulates rat uterine smooth muscle contraction, and gastrin and somatostatin secretion in vitro. Increases blood pressure and pancreatic exocrine secretion in dogs in vivo.
分子量 | 1120.29 |
公式 | C50H73N17O11S |
序列 |
GNHWAVGHLM (Modifications: Met-10 = C-terminal amide) |
储存 | Desiccate at -20°C |
CAS Number | 81608-30-2 |
Smiles | [H]NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Hosotani et al (1985) Effect of synthetic neuromedin C, a decapeptide of gastrin-releasing peptide (GRP[18-27]), on blood flow and exocrine secretion of the pancreas in dogs. Life Sci. 36 2429 PMID: 3892215
Madaus et al (1989) Effect of gastrin-releasing peptide (GRP1-27), neuromedin-C (GRP18-27), and neuromedin-B on gastrin and somatostatin secretion from the rat stomach. Z.Gastroenterol. 27 449 PMID: 2573979
Minamino et al (1984) Neuromedin C: a bombesin-like peptide identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 119 14 PMID: 6546686
关键词: Neuromedin C (porcine), Neuromedin C (porcine) supplier, Mammalian, bombesin-like, peptide, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, NeuromedinC, (porcine), GRP, (18-27), 1890, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.