Melittin

Pricing Availability   Qty
Cat.No. 1193 - Melittin | Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 | CAS No. 20449-79-0
说明: Inhibits Gs and stimulates Gi activity
说明书
引用文献 (1)
评论
文献 (2)

生物活性 for Melittin

Melittin is a inhibits Gs and stimulates Gi activity. Inhibits protein kinase C and cAMP-dependent protein kinases. Na+/K+ ATPase inhibitor.

技术数据 for Melittin

分子量 2847
公式 C131H229N39O31
序列 GIGAVLKVLTTGLPALISWIKRKRQQ

(Modifications: Gln-26 = C-terminal amide)

储存 Desiccate at -20°C
CAS Number 20449-79-0
PubChem ID 16133648
InChI Key VDXZNPDIRNWWCW-JFTDCZMZSA-N
Smiles [H]NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Melittin

溶解性 Soluble to 1 mg/ml in water

产品说明书 for Melittin

分析证书/产品说明书
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参考文献 for Melittin

参考文献是支持产品生物活性的出版物。

Fukushima et al (1998) Melittin, a metabostatic peptide inhibiting Gs activity. Peptides 5 811 PMID: 9663445

Mousli et al (1990) G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. TiPS 11 358 PMID: 2122563

Raynor et al (1991) Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin. J.Biol.Chem. 266 2753 PMID: 1847132


If you know of a relevant reference for Melittin, please let us know.

关键词: Melittin, Melittin supplier, Inhibitors, inhibits, Gs, stimulates, stimulators, Gi, activity, protein, kinases, C, cAMP-dependent, G, Proteins, Heterotrimeric, PKC, G-protein, GTPases, Protein, Kinase, 1193, Tocris Bioscience

1 篇 Melittin 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Melittin 的部分引用包括:

Meitzen et al (2011) β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons. J Neurochem 116 984 PMID: 21143600


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