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Submit ReviewLF 11
说明： Antibiotic; neutralizes LPS
生物活性 for LF 11
LF 11 is a peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. Neutralizes LPS; displays antimicrobial activity against Gram-negative and Gram-positive bacteria. Analog lauryl-LF 11 (Cat. No. 4422) available.
技术数据 for LF 11
| 分子量 | 1529.81 |
| 公式 | C69H112N26O14 |
| 序列 |
FQWQRNIRKVR (Modifications: Arg-11 = C-terminal amide) |
| 储存 | Store at -20°C |
| CAS Number | 832729-13-2 |
| PubChem ID | 25089955 |
| InChI Key | SIROSQHTQDVQTI-JDJCIBPGSA-N |
| Smiles | [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for LF 11
参考文献 for LF 11
参考文献是支持产品生物活性的出版物。
Sanchez-Gomez et al (2008) Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides. BMC Mirobiol. 11 196 PMID: 19014450
Japelj et al (2005) Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide. J.Biol.Chem. 280 16955 PMID: 15687491
Andra et al (2005) Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 385 135 PMID: 15344905
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关键词: LF 11, LF 11 supplier, LF11, lps, lipopolysaccharide, lactoferricin, antimicrobial, peptide, antibiotics, Antibiotics, 4421, Tocris Bioscience
LF 11 的评论
平均评分: 5 (Based on 1 Review.)
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Highly resistant E.Coli produced through gene transfer were subjected to LF 11.
By
Anonymous on 12/13/2018
种属： Human
Highly resistant E.Coli produced through gene transfer were subjected to LF 11 and few other antibiotics to assess the antimicrobial activity over the resistant strains.The percentage inhibition over time was determined by disc diffusion and broth dilution methods.
