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Submit ReviewLauryl-LF 11 is a N-terminally acylated analog of LF 11 (Cat. No. 4421). Displays enhanced antibacterial and LPS-binding activities.
分子量 | 1712.11 |
公式 | C81H134N26O15 |
序列 |
FQWQRNIRKVR (Modifications: Phe-1 = CH3-(CH2)10-CO-NH-Phe, Arg-11 = C-terminal amide) |
储存 | Store at -20°C |
CAS Number | 832729-14-3 |
PubChem ID | 90488941 |
InChI Key | AUHGQKBFMDAWAQ-BSHYLFJSSA-N |
Smiles | CCCCCCCCCCCNC(CC1CCCCC1)C(O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)CN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Zweytick et al (2006) Influence of N-acylation of a peptide derived from human lactoferricin on membrane selectivity. Biochim.Biophys.Acta 1758 1426 PMID: 16616888
Rosenfeld et al (2010) Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides. Biochemistry 49 853 PMID: 20058937
Andra et al (2005) Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 385 135 PMID: 15344905
关键词: Lauryl-LF 11, Lauryl-LF 11 supplier, lauryl-LF11, lps, lipopolysaccharide, lactoferricin, antimicrobial, peptides, antibiotics, Antibiotics, 4422, Tocris Bioscience
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