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Submit ReviewGalanin (porcine)
说明： Galanin receptor agonist
生物活性 for Galanin (porcine)
Galanin (porcine) is an endogenous porcine galanin receptor agonist (pKi values are 9.63, 9.49, 9.02, 8.98, 8.01 and 8.14 at hGAL1, rGAL1, hGAL2, rGAL2, hGAL3 and rGAL3 respectively). Significantly increases food intake under free access conditions and also has roles in learning and memory, anxiety and sexual behavior.
技术数据 for Galanin (porcine)
| 分子量 | 3210.55 |
| 公式 | C146H213N43O40 |
| 序列 |
GWTLNSAGYLLGPHAIDNHRSFHDKYGLA (Modifications: Ala-29 = C-terminal amide) |
| 储存 | Desiccate at -20°C |
| CAS Number | 88813-36-9 |
| PubChem ID | 16133811 |
| InChI Key | SLZIZIJTGAYEKK-CIJSCKBQSA-N |
| Smiles | [H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Galanin (porcine)
参考文献 for Galanin (porcine)
参考文献是支持产品生物活性的出版物。
Brewer and Robinson (2008) Galanin stimulation of feeding is blocked by the addition of a response element. Behav.Neurosci. 122 949 PMID: 18729649
Branchek et al (2000) Galanin receptor subtypes. TiPS. 21 109
Tachibana et al (2008) Central administration of galanin stimulates feeding behavior in chicks. Comp.Biochem.Physiol.A.Mol.Inter.Physiol. 151 637
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关键词: Galanin (porcine), Galanin (porcine) supplier, Galanin, receptor, agonists, GAL, Receptors, 3008, Tocris Bioscience
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该领域的文献
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.