D-(+)-threo-3-Hydroxyaspartic acid

Discontinued Product

0182 has been discontinued.

View all Glutamate (EAAT) Transporters products.
说明: Potent,competitive, transportable inhibitor of L-glutamate and L-aspartate uptake
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生物活性 for D-(+)-threo-3-Hydroxyaspartic acid

Potent, competitive, transportable inhibitor of L-glutamate and L-aspartate uptake. Less active than (L)-isomer (Cat. No. 0183).

技术数据 for D-(+)-threo-3-Hydroxyaspartic acid

分子量 149.1
储存 Store at RT
CAS Number 16417-36-0

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

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参考文献 for D-(+)-threo-3-Hydroxyaspartic acid

参考文献是支持产品生物活性的出版物。

Johnston et al (1980) Potentiation of L-glutamate and L-aspartate excitation of cat spinal neurones by the stereoisomers of threo-3-hydroxyaspartate. J.Neurochem. 34 241 PMID: 7452241

McBean and Roberts (1985) Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum. J.Neurochem. 44 247 PMID: 2856883

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关键词: D-(+)-threo-3-Hydroxyaspartic acid, D-(+)-threo-3-Hydroxyaspartic acid supplier, Glutamate, Transporters, 0182, Tocris Bioscience

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Huntington's Disease Poster

Huntington's Disease Poster

Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.