Bicifadine hydrochloride

Name: Bicifadine hydrochloride
Brand: Tocris Bioscience
SKU: 4357

Cat. No. 4357 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4357 has been discontinued.

View all Adrenergic Transporters products.

说明： Noradrenalin, 5-HT and dopamine re-uptake inhibitor

化学名： 1-(4-Methylphenyl)-3-azabicyclo[3.1.0]hexane hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Bicifadine hydrochloride

Bicifadine hydrochloride is a potent antagonist of the noradrenalin transporter (IC₅₀ = 55 nM); also displays antagonist activity at the 5-HT and dopamine transporters (IC₅₀ values are 117 nM and 910 nM respectively). Orally active. Exhibits antinociceptive and antiallodynic activity in rodent models of acute, persistent, and chronic pain.

技术数据 for Bicifadine hydrochloride

分子量	209.72
公式	C₁₂H₁₅N.HCl
储存	Desiccate at RT
纯度	≥98% (HPLC)
CAS Number	66504-75-4
PubChem ID	47952
InChI Key	OTZOPAFTLUOBOM-UHFFFAOYSA-N
Smiles	CC(C=C3)=CC=C3C12CNCC1C2.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Bicifadine hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Bicifadine hydrochloride

参考文献是支持产品生物活性的出版物。

Epstein (1981) 1-Aryl-3-azabicyclo[3.1.0]hexanes, a new series of nonnarcotic analgesic agents. J.Med.Chem. 24 481 PMID: 7241504

Basile (2007) Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain. J.Pharmacol.Exp.Ther 321 1208 PMID: 17325229

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篇 Bicifadine hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。

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