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说明： 5-, 12-, 15-Lipoxygenase inhibitor
化学名： 2-(1-Thienyl)ethyl 3,4-dihydroxybenzylidenecyanoacetate
纯度： ≥99% (HPLC)
生物活性 for 2-TEDC
2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase (IC50 values are 0.09, 0.013 and 0.5 μM respectively).
技术数据 for 2-TEDC
| 分子量 | 315.34 |
| 公式 | C16H13NO4S |
| 储存 | Desiccate at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 132465-10-2 |
| PubChem ID | 6069552 |
| InChI Key | KCGLTUBCAGZLHP-XYOKQWHBSA-N |
| Smiles | OC1=C(O)C=C(\C=C(/C#N)C(=O)OCCC2=CC=CS2)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for 2-TEDC
参考文献 for 2-TEDC
参考文献是支持产品生物活性的出版物。
Cho et al (1991) Novel caffeic acid derivatives - extremely potent inhibitors of 12-lipoxygenase. J.Med.Chem. 34 1503 PMID: 2016727
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关键词: 2-TEDC, 2-TEDC supplier, 5-lipoxygenase, 12-lipoxygenase, 15-Lipoxygenase, inhibitors, inhibits, Oxygenases, Oxidases, 5-LOX, 12-LOX, 15-LOX, Lipoxygenase, 0645, Tocris Bioscience
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