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说明： Modulates AMPA-mediated responses
化学名： 1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine
纯度： ≥99% (HPLC)
生物活性 for 1-BCP
A centrally active selective potentiator of AMPA-mediated responses. Facilitates memory retention in rats.
技术数据 for 1-BCP
| 分子量 | 233.27 |
| 公式 | C13H15NO3 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 34023-62-6 |
| PubChem ID | 1370 |
| InChI Key | BXBNADAPIHHXJQ-UHFFFAOYSA-N |
| Smiles | O=C(N1CCCCC1)C1=CC2=C(OCO2)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for 1-BCP
参考文献 for 1-BCP
参考文献是支持产品生物活性的出版物。
Arai et al (1994) A centrally active drug that modulates AMPA receptor gated currents. Brain Res. 638 343 PMID: 7911064
Desai et al (1995) 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]NE release in rat hippocampal slices. Neuropharmacology 34 141 PMID: 7542369
Vanove (1997) Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion. Eur.J.Pharmacol. 332 115 PMID: 9286612
Yamada et al (1998) AMPA receptor activation potentiated by the AMPA modulator 1-BCP is toxic to cultured rat hippocampal neurons. Neurosci.Lett. 249 119 PMID: 9682831
关键词: 1-BCP, 1-BCP supplier, Modulates, AMPA-mediated, responses, Glutamate, Receptors, iGlur, Ionotropic, AMPA, 1048, Tocris Bioscience
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