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Submit ReviewVirodhamine trifluoroacetate is a TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist that is found in higher concentrations peripherally than anandamide. Virodhamine is a full agonist at GPR55 and CB2 and partial agonist/antagonist at CB1 (EC50 values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively).
| 分子量 | 461.56 |
| 公式 | C22H37NO2.CF3CO2H |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 1415264-56-0 |
| PubChem ID | 91691131 |
| InChI Key | APQWCQIPZHJFAU-XVSDJDOKSA-N |
| Smiles | O=C(OCCN)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC.FC(F)(F)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Porter et al (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J.Pharmacol.Exp.Ther. 301 1020 PMID: 12023533
关键词: Virodhamine trifluoroacetate, Virodhamine trifluoroacetate supplier, Virodhamine, TFA, GPR55, CB2, agonists, CB1, partial, antagonists, non-selective, cannabinoids, receptors, cb2r, cb1r, Trifluoroacetic, acid, salt, Non-selective, Cannabinoids, 5395, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Virodhamine trifluoroacetate 的部分引用包括:
Hayase (2013) Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. BMC Neurosci 14 20 PMID: 23394117
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