Virodhamine trifluoroacetate

Discontinued Product

5395 has been discontinued.

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说明: TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist
化学名: O-(2-Aminoethyl)-5Z,8Z,11Z,14Z-eicosatetraenoate trifluoroacetate
纯度: ≥98% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)

生物活性 for Virodhamine trifluoroacetate

Virodhamine trifluoroacetate is a TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist that is found in higher concentrations peripherally than anandamide. Virodhamine is a full agonist at GPR55 and CB2 and partial agonist/antagonist at CB1 (EC50 values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively).

技术数据 for Virodhamine trifluoroacetate

分子量 461.56
公式 C22H37NO2.CF3CO2H
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1415264-56-0
PubChem ID 91691131
InChI Key APQWCQIPZHJFAU-XVSDJDOKSA-N
Smiles O=C(OCCN)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC.FC(F)(F)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Virodhamine trifluoroacetate

参考文献 for Virodhamine trifluoroacetate

参考文献是支持产品生物活性的出版物。

Porter et al (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J.Pharmacol.Exp.Ther. 301 1020 PMID: 12023533

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1 篇 Virodhamine trifluoroacetate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Virodhamine trifluoroacetate 的部分引用包括:

Hayase (2013) Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. BMC Neurosci 14 20 PMID: 23394117


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Cannabinoid Receptor Ligands Scientific Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.