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Submit ReviewSHIP 2a
说明： Cystathione γ lyase (CSE) inhibitor
化学名： (R)-2-Oxo-N-2-propyn-1-yl-4-thiazolidinecarboxamide
纯度： ≥98% (HPLC)
生物活性 for SHIP 2a
SHIP 2a is a cystathione γ lyase (CSE) inhibitor (IC50 = 6.3 μM). Inhibits H2S production in mouse aorta homogenates and L-cysteine-induced relaxation of rat aortic rings ex vivo.
技术数据 for SHIP 2a
| 分子量 | 184.22 |
| 公式 | C7H8N2O2S |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 2165706-30-7 |
| PubChem ID | 124221753 |
| InChI Key | MWEQVHWJNCRXGP-YFKPBYRVSA-N |
| Smiles | O=C([C@@H]1CSC(N1)=O)NCC#C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for SHIP 2a
参考文献 for SHIP 2a
参考文献是支持产品生物活性的出版物。
Corvino et al (2016) Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production. Sci.Rep. 6 34398 PMID: 27708394
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关键词: SHIP 2a, SHIP 2a supplier, SHIP2a, cystathionase, cystathione, gamma, lyase, CSE, γ, inhibitors, inhibits, hydrogen, sulphide, sulfide, H2S, Other, Lyases, 6101, Tocris Bioscience
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