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Submit ReviewRU 26752
说明： Mineralocorticoid receptor antagonist
化学名： (7α,17α)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid γ-lactone
纯度： ≥99% (HPLC)
生物活性 for RU 26752
Mineralocorticoid receptor antagonist. Prevents aldosterone-induced hypertension in rats.
技术数据 for RU 26752
| 分子量 | 384.55 |
| 公式 | C25H36O3 |
| 储存 | Store at -20°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 76676-33-0 |
| PubChem ID | 9886385 |
| InChI Key | MOFIIHQCTIJVBB-JEHIOXJOSA-N |
| Smiles | O=C1CC[C@@]2(C)C(C[C@@H](CCC)[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@]54OC(CC5)=O)=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for RU 26752
参考文献 for RU 26752
参考文献是支持产品生物活性的出版物。
Kalimi et al (1990) Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. Am.J.Physiol. 258 E737 PMID: 2333987
Huyet et al (2007) Structural basis of spirolactone recognition by the mineralocorticoid receptor. Mol.Pharmacol. 72 563 PMID: 17569793
Lazar and Agarwal (1986) Evidence for an antagonist specific receptor that does not bind mineralocorticoid agonists. Biochem.Biophy.Res.Comms. 134 261
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关键词: RU 26752, RU 26752 supplier, Mineralocorticoid, receptors, antagonists, Aldosterone, RU26752, Receptor, 2970, Tocris Bioscience
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