RU 26752

Discontinued Product

2970 has been discontinued.

View all Mineralocorticoid Receptors products.
说明: Mineralocorticoid receptor antagonist
化学名: (7α,17α)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid γ-lactone
纯度: ≥99% (HPLC)
说明书
引用文献
评论

生物活性 for RU 26752

Mineralocorticoid receptor antagonist. Prevents aldosterone-induced hypertension in rats.

技术数据 for RU 26752

分子量 384.55
公式 C25H36O3
储存 Store at -20°C
纯度 ≥99% (HPLC)
CAS Number 76676-33-0
PubChem ID 9886385
InChI Key MOFIIHQCTIJVBB-JEHIOXJOSA-N
Smiles O=C1CC[C@@]2(C)C(C[C@@H](CCC)[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@]54OC(CC5)=O)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for RU 26752

参考文献是支持产品生物活性的出版物。

Kalimi et al (1990) Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. Am.J.Physiol. 258 E737 PMID: 2333987

Huyet et al (2007) Structural basis of spirolactone recognition by the mineralocorticoid receptor. Mol.Pharmacol. 72 563 PMID: 17569793

Lazar and Agarwal (1986) Evidence for an antagonist specific receptor that does not bind mineralocorticoid agonists. Biochem.Biophy.Res.Comms. 134 261

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关键词: RU 26752, RU 26752 supplier, Mineralocorticoid, receptors, antagonists, Aldosterone, RU26752, Receptor, 2970, Tocris Bioscience

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