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Submit ReviewMineralocorticoid receptor antagonist. Prevents aldosterone-induced hypertension in rats.
分子量 | 384.55 |
公式 | C25H36O3 |
储存 | Store at -20°C |
纯度 | ≥99% (HPLC) |
CAS Number | 76676-33-0 |
PubChem ID | 9886385 |
InChI Key | MOFIIHQCTIJVBB-JEHIOXJOSA-N |
Smiles | O=C1CC[C@@]2(C)C(C[C@@H](CCC)[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@]54OC(CC5)=O)=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Kalimi et al (1990) Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. Am.J.Physiol. 258 E737 PMID: 2333987
Huyet et al (2007) Structural basis of spirolactone recognition by the mineralocorticoid receptor. Mol.Pharmacol. 72 563 PMID: 17569793
Lazar and Agarwal (1986) Evidence for an antagonist specific receptor that does not bind mineralocorticoid agonists. Biochem.Biophy.Res.Comms. 134 261
关键词: RU 26752, RU 26752 supplier, Mineralocorticoid, receptors, antagonists, Aldosterone, RU26752, Receptor, 2970, Tocris Bioscience
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