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p-DITC-APEC

Cat. No. 2405 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2405 has been discontinued.

View all Adenosine A<sub>2A</sub> Receptors products.
说明： Irreversible A2A agonist
化学名： 2-[4-[2-[2-[(4-Isothiocyanatophenyl)thiocarbonylamino]ethylaminocarbonyl]ethyl]phenethylamino]-5'-N-ethylcarboxamidadenosine
纯度： ≥95% (HPLC)
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引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for p-DITC-APEC

Irreversible A2A receptor agonist (apparent Ki = 9.9 nM). Displays > 8-fold selectivity for A2 versus A1 receptors (Ki values are 35 and 276 nM for rat A2 and A1 receptors respectively). Produces progressive concentration-independent vasodilation in guinea pig heart Langendorff preparations.

技术数据 for p-DITC-APEC

分子量 733.86
公式 C33H39N11O5S2
储存 Store at -20°C
纯度 ≥95% (HPLC)

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for p-DITC-APEC

分析证书目前不在网上提供。
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化学品安全技术说明书

参考文献 for p-DITC-APEC

参考文献是支持产品生物活性的出版物。

Jacobson et al (1992) Chemical modification and irreversible inhibition of striatal A2A adenosine receptors. Mol.Pharmacol. 42 123 PMID: 1635550

Jacobson et al (1989) Agonist derived molecular probes for A2 adenosine receptors. J.Mol.Recog. 2 170

Niiya et al (1993) Covalent binding of a selective agonist irreversibly activates guinea pig coronary artery A2 adenosine receptors. Naunyn-Schmied.Arch.Pharmacol. 347 521

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关键词: p-DITC-APEC, p-DITC-APEC supplier, A2A, adenosines, agonist, Adenosine, Receptors, 2405, Tocris Bioscience

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