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View all Heterotrimeric G-protein GTPases products.Amphiphilic G protein activator peptide that forms a-helices in lipid membranes; more potent and efficacious than mastoparan (Cat. No. 1192). Inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki = 2.2 mM). Also induces cation-permeable pore formation and Ca2+ influx in SK-N-BE(2)C cells.
分子量 | 1421.83 |
公式 | C67H124N18O15 |
储存 | Desiccate at -20°C |
CAS Number | 145854-59-7 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Higashijima et al (1990) Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. J.Biol.Chem. 265 14176 PMID: 2117607
Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799 PMID: 10329678
Suh et al (1996) Induction of cytosolic Ca2+ elevation mediated by Mas-7 occurs through membrane pore formation. J.Biol.Chem. 271 32753 PMID: 8955110
关键词: Mastoparan -7, Mastoparan -7 supplier, Amphiphilic, G, protein, activator, peptide, that, forms, a-helices, in, lipid, membranes;, more, potent, and, efficacious, than, mastoparan, (Cat., No., 1192)., Inhibits, sarcoplasmic, reticulum, Ca2+-ATPase, (Ki, =, 2.2, mM)., Also, induces, cation-permeable, pore, formation, Ca2+, infl, Mas, 7, Heterotrimeric, G-protein, GTPases, 1895, Tocris Bioscience
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