L-NMMA acetate

Discontinued Product

0771 has been discontinued.

View all Non-selective NOS products.
说明: Non-selective NOS inhibitor
化学名: NG-Monomethyl-L-arginine acetate
说明书
引用文献 (6)
评论

生物活性 for L-NMMA acetate

L-NMMA acetate is a competitive, irreversible inhibitor of all three NOS isoforms.

技术数据 for L-NMMA acetate

分子量 248.28
公式 C7H16N4O2.CH3CO2H
储存 Desiccate at RT
CAS Number 53308-83-1
PubChem ID 135242
InChI Key IKPNWIGTWUZCKM-JEDNCBNOSA-N
Smiles CC(O)=O.N=C(NCCC[C@H](N)C(O)=O)NC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for L-NMMA acetate

分析证书/产品说明书
选择另一批次:

参考文献 for L-NMMA acetate

参考文献是支持产品生物活性的出版物。

Olken et al (1991) Inactivation of macrophage nitric oxide synthase activity by N(G)-methyl-L-arginine. Biochem.Biophys.Res.Commun. 177 828 PMID: 2049105

Rees et al (1990) Characterisation of three inhibitors of endothelial nitric oxide synthase in vivo and in vitro. Br.J.Pharmacol. 101 746 PMID: 1706208

Reif and McCreedy et al (1995) N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a differential pattern of inactivation toward the three nitric oxide synthases. Arch.Biochem.Biophys. 320 170 PMID: 7540822

Saksuma et al (1988) Identification of arginine as a precursor of endothelium-derived relaxing factor. Proc.Natl.Acad.Sci.U.S.A. 85 8664 PMID: 3263652

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关键词: L-NMMA acetate, L-NMMA acetate supplier, Non-Selective, NOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, NO, Synthases, nNOS, iNOS, eNOS, Non-selective, 0771, Tocris Bioscience

6 篇 L-NMMA acetate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 L-NMMA acetate 的部分引用包括:

Echeverría et al (2014) Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity. PLoS One 9 e94146 PMID: 24710004

Carlile et al (2012) An anxiolytic-like effect of hyperbaric oxygen in the mouse light/dark exploration test. Life Sci 90 267 PMID: 22154905

Schophuizen et al (2015) Uremic Toxins Induce ET-1 Release by Human Proximal Tubule Cells, which Regulates Organic Cation Uptake Time-Dependently. J Neurosci 4 234 PMID: 26132391

Queval et al (2016) STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection. Sci Rep 6 29297 PMID: 27384401


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