Fenofibrate

Discontinued Product

4113 has been discontinued.

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说明: PPARα agonist
化学名: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester
纯度: ≥99% (HPLC)
说明书
引用文献 (5)
评论

生物活性 for Fenofibrate

Fenofibrate is a PPARα agonist; hypolipidemic. Attenuates insulin resistance and increases high-density lipoprotein-cholesterol in db/db mice.

化合物库 for Fenofibrate

Fenofibrate is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。

技术数据 for Fenofibrate

分子量 360.83
公式 C20H21ClO4
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 49562-28-9
PubChem ID 3339
InChI Key YMTINGFKWWXKFG-UHFFFAOYSA-N
Smiles CC(C)OC(C(C)(C)OC(C=C2)=CC=C2C(C1=CC=C(Cl)C=C1)=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Fenofibrate

分析证书/产品说明书
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参考文献 for Fenofibrate

参考文献是支持产品生物活性的出版物。

Mandard et al (2004) The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofi. treatment. J.Biol.Chem. 279 34411 PMID: 15190076

Park et al (2006) PPARα agonist fenofi. improves diabetic nephropathy in db/db mice. Kidney Int. 69 1511 PMID: 16672921

Balakumar et al (2011) Pleiotropic actions of fenofi. on the heart. Pharmacol.Res. 63 8 PMID: 21093591

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关键词: Fenofibrate, Fenofibrate supplier, peroxisome, proliferator-activated, receptors, pparalpha, PPARa, PPARα, agonists, PPARalpha, Receptors, 4113, Tocris Bioscience

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