DAU 5884 hydrochloride

Name: DAU 5884 hydrochloride
Brand: Tocris Bioscience
SKU: 2096

Cat. No. 2096 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2096 has been discontinued.

View all M<sub>3</sub> Receptors products.

说明： M₃ receptor antagonist

化学名： 8-Methyl-8-azabicyclo-3-endo[3.2.1]oct-3-yl-1,4-dihydro-2-oxo-3(2H)-quinazolinecarboxylic acid ester hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献 (1)

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for DAU 5884 hydrochloride

DAU 5884 hydrochloride is a selective muscarinic M₃ receptor antagonist. In bovine tracheal smooth muscle, inhibits methacholine-dependent effects on cell proliferation and muscle contractility.

技术数据 for DAU 5884 hydrochloride

分子量	351.83
公式	C₁₇H₂₁N₃O₃.HCl
储存	Desiccate at +4°C
纯度	≥98% (HPLC)
CAS Number	131780-48-8
PubChem ID	16759154
InChI Key	FDERDDSQHZRNGC-LIWIJTDLSA-N
Smiles	Cl.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)N1CC2=C(NC1=O)C=CC=C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for DAU 5884 hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for DAU 5884 hydrochloride

参考文献是支持产品生物活性的出版物。

Doods et al (1993) Characterization of muscarinic receptors in guinea-pig uterus. Eur.J.Pharmacol. 250 223 PMID: 8112383

Roffel et al (1993) Cholinergic contraction of the guinea pig lung strip is mediated by muscarinic M₂-like receptors. Eur.J.Pharmacol. 250 267 PMID: 8112384

Gosens et al (2003) Muscarinic M₃-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. Am.J.Respir.Cell Mol.Biol. 28 257 PMID: 12540494

Gosens et al (2004) Muscarinic M₃ receptor-dependent regulation of airway smooth muscle contractile phenotype. Br.J.Pharmacol. 141 943 PMID: 14993104

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关键词: DAU 5884 hydrochloride, DAU 5884 hydrochloride supplier, M3, receptor, antagonists, Muscarinic, Receptors, Acetylcholine, ACh, DAU5884, hydrochloride, 2096, Tocris Bioscience

1 篇 DAU 5884 hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 DAU 5884 hydrochloride 的部分引用包括：

Zhu et al (2017) Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses. Nat Commun 8 1676 PMID: 29162816