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Submit ReviewCID 1375606
说明： GPR27 agonist
化学名： 2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide
纯度： ≥98% (HPLC)
生物活性 for CID 1375606
CID 1375606 is a GPR27 agonist. Promotes recruitment of β-arrestin 2 to chimeric GPR27V2 and wild-type GPR27 in a firefly luciferase complementation assay (pEC50 values are 6.34 and 5.1, respectively).
化合物库 for CID 1375606
CID 1375606 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。
技术数据 for CID 1375606
| 分子量 | 385.24 |
| 公式 | C20H14Cl2N2O2 |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 313493-80-0 |
| PubChem ID | 1375606 |
| InChI Key | PFHDXBXPRBQVAV-UHFFFAOYSA-N |
| Smiles | ClC1=CC(Cl)=C(C(NC2=CC=C(C(NC3=CC=CC=C3)=O)C=C2)=O)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for CID 1375606
参考文献 for CID 1375606
参考文献是支持产品生物活性的出版物。
Dupuis et al (2017) Activation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment. Mol.Pharmacol. 91 595 PMID: 28314853
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关键词: CID 1375606, CID 1375606 supplier, GPR27, agonists, agonism, SREB1, CID11375606, Orphan, 7-TM, Receptors, 6544, Tocris Bioscience
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