CALP2

Name: CALP2
Brand: Tocris Bioscience
SKU: 2319

Cat. No. 2319 4 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2319 has been discontinued.

View all Calcium Binding Proteins products.

说明： Cell-permeable calmodulin antagonist

别名： Calcium-like peptide 2

说明书

引用文献 (4)

生物活性技术数据说明书参考文献

生物活性 for CALP2

CALP2 is a cell-permeable calmodulin (CaM) antagonist that binds to the EF-hand/Ca²⁺-binding site. CALP2 has been demonstrated to inhibit CaM-dependant phosphodiesterase activity and increase intracellular Ca²⁺ concentrations by modulating Ca²⁺-channel activity. CALP2 has also been shown to be a potent activator of alveolar macrophages.

技术数据 for CALP2

分子量	1357.72
公式	C₆₈H₁₀₄N₁₄O₁₃S
序列	VKFGVGFKVMVF
储存	Desiccate at -20°C
CAS Number	261969-04-4
PubChem ID	90471211
InChI Key	ODWOEJYNFFTQOH-IVGXUUFVSA-N
Smiles	[H]N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for CALP2

分析证书/产品说明书

化学品安全技术说明书

参考文献 for CALP2

参考文献是支持产品生物活性的出版物。

Houtman et al (2001) Attenuation of very late antigen-5-mediated adhesion of bone marrow-derived mast cells to fibronectin by peptides with inverted hydropathy to EF-hands. J.Immunol. 166 861 PMID: 11145661

Ten Broeke et al (2001) Calcium sensors as new therapeutic targets for airway hyperresponsiveness and asthma. FASEB J. 15 1831 PMID: 11481245

Ten Broeke et al (2004) Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages. Lab.Invest. 84 29 PMID: 14631377

Villain et al (2000) De novo design of peptides targeted to the EF hands of calmodulin. J.Biol.Chem. 274 2676

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关键词: CALP2, CALP2 supplier, Cell-permeable, calmodulin, antagonists, Ca2+, Binding, Protein, modulators, Calcium, Signaling, Signalling, Calcium-like, peptide2, peptide, 2, 2319, Tocris Bioscience