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Submit ReviewBAY-u 9773
Discontinued Product
3138 has been discontinued.
View all Leukotriene and Related Receptors products.
说明： Dual CysLT1 and CysLT2 antagonist
化学名： 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoic acid
生物活性 for BAY-u 9773
Cysteinyl leukotriene receptor antagonist with equal affinity at both CysLT1 and CysLT2 receptors (pKB values are 6.8 and 6.5 respectively). Competitive antagonist of LTC4- and LTE4-induced contractions of the guinea pig trachea.
技术数据 for BAY-u 9773
| 分子量 | 472.64 |
| 公式 | C27H36O5S |
| 储存 | Store at -80°C |
| CAS Number | 154978-38-8 |
| PubChem ID | 5311015 |
| InChI Key | PKJINWOACFYDQN-RBVMPENBSA-N |
| Smiles | CCCCC\C=C/C/C=C\C=C\C=C\[C@@H](SC1=CC=C(C(O)=O)C=C1)[C@@H](O)CCCC(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for BAY-u 9773
参考文献 for BAY-u 9773
参考文献是支持产品生物活性的出版物。
Labat et al (1992) A second cysteinyl leukotriene receptor in human lung. J.Pharmacol.Exp.Ther. 263 800 PMID: 1331415
Goranne et al (1996) Cysteinyl leukotriene receptors in the human lung: what's new? TiPS 17 342 PMID: 8979767
Back (2002) Functional characteristics of cysteinyl-leukotriene receptor subtypes. Life Sci. 71 611 PMID: 12072150
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关键词: BAY-u 9773, BAY-u 9773 supplier, Dual, CysLT1, CysLT2, antagonists, Receptors, leukotrienes, eicosanoids, BAY-u9773, Leukotriene, and, Related, 3138, Tocris Bioscience
1 篇 BAY-u 9773 的引用文献
引用文献是使用了 Tocris 产品的出版物。 BAY-u 9773 的部分引用包括：
Wegner et al (2019) Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. Elife 8 PMID: 30838976
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