α-helical CRF 9-41

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Cat.No. 1184 - alpha-helical CRF 9-41 | Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2 | CAS No. 90880-23-2
说明: CRF antagonist
别名: α-helical-Corticotropin-Releasing Factor 9-41
纯度: ≥95% (HPLC)
说明书
引用文献 (2)
评论 (1)
文献 (3)

生物活性 for α-helical CRF 9-41

α-helical CRF 9-41 is a corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).

许可信息

Sold with the permission of the SALK Institute

技术数据 for α-helical CRF 9-41

分子量 3827
公式 C166H274N46O53S2
序列 DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA

(Modifications: Ala-33 = C-terminal amide)

储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 90880-23-2
PubChem ID 44593730
InChI Key PNGVJHODDQMQKT-GVKLFNHCSA-N
Smiles [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for α-helical CRF 9-41

溶解性 Soluble to 1 mg/ml in 0.1M NH4OH

产品说明书 for α-helical CRF 9-41

分析证书/产品说明书
选择另一批次:

参考文献 for α-helical CRF 9-41

参考文献是支持产品生物活性的出版物。

Kask et al (1997) Alpha-helical(9-41) revents anxiogenic-like effect of NPY Y1 receptor antagonist BIBP3226. NeuroReport 8 3645 PMID: 9427342

Perrin and Vale (1999) Corticotropin releasing factor receptors and their ligand family. Ann.N.Y.Acad.Sci. 885 312 PMID: 10816663

Swerdlow et al (1989) Potentiation of acoustic startle by corticotropin-releasing factor (CRF) and by fear are both reversed by α-helical CRF (9-41). Neuropsychopharmacology 2 285 PMID: 2610824


If you know of a relevant reference for α-helical CRF 9-41, please let us know.

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查看全部 Non-selective CRF Receptor Antagonists

关键词: alpha-helical CRF 9-41, alpha-helical CRF 9-41 supplier, CRF, receptor, antagonists, Corticotropin-Releasing, Factor, Non-Selective, Receptors, α-helical, alpha-helical, 9-41, a-helical, CRF9-41, a-helical-Corticotropin-Releasing, Factor9-41, Non-selective, 1184, Tocris Bioscience

2 篇 α-helical CRF 9-41 的引用文献

引用文献是使用了 Tocris 产品的出版物。 α-helical CRF 9-41 的部分引用包括:

Wang et al (2014) Involvement of CRH and hCG in the induction of aromatase by cortisol in human placental syncytiotrophoblasts. Placenta 35 30 PMID: 24239159

Jia et al (2013) Role of nesfatin-1 in a rat model of visceral hypersensitivity. J Immunol 19 3487 PMID: 23801843


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α-helical CRF 9-41 的评论

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cell treatment.
By Anonymous on 05/31/2018
分析类型: In Vitro
种属: Human
细胞系/组织: placental cytotrophoblast

cell treatment


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