26RFa

Discontinued Product

4402 has been discontinued.

View all Orphan 7-TM Receptors products.
说明: Ligand of GPR103; orexigenic neuropeptide
别名: P518,QRFP
说明书
引用文献 (1)
评论

生物活性 for 26RFa

Hypothalamic RFamide-related neuropeptide. Acts as a natural ligand of the orphan receptor GPR103. Exhibits orexigenic acitivity in mice upon central administration.

技术数据 for 26RFa

分子量 2818.18
公式 C127H197N37O36
序列 VGTALGSLAEELNGYNRKKGGFSFRF

(Modifications: Phe-26 = C-terminal amide)

储存 Store at -20°C
CAS Number 881640-56-8
PubChem ID 90488938
InChI Key QPWYMHBRJDWMIS-AULSSRMGSA-N
Smiles [H]N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for 26RFa

参考文献是支持产品生物活性的出版物。

Kampe et al (2006) Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat. Brain Res. 1119 133 PMID: 16996040

Le Marec et al (2011) Structure-activity relationships of a series of analogues of the RFamide-related peptide 26RFa J.Med.Chem. 54 4806 PMID: 21623631

Chartrel et al (2003) Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity. Proc.Natl.Acad.Sci.USA 100 15247 PMID: 14657341

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关键词: 26RFa, 26RFa supplier, rfrp, GPR103, ligands, neuropeptides, orexigenic, appetite, stimulating, stimulators, qrfpr, P518, QRFP, Orphan, 7-TM, Receptors, Other, Peptide, 4402, Tocris Bioscience

1 篇 26RFa 的引用文献

引用文献是使用了 Tocris 产品的出版物。 26RFa 的部分引用包括:

Nøhr et al (2017) The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW. Neurochem Int 102 105 PMID: 27916541


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