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Submit ReviewRemodelin
说明： N-acetyltransferase 10 (NAT10) inhibitor
化学名： 4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile
纯度： ≥99% (HPLC)
生物活性 for Remodelin
Remodelin is a N-acetyltransferase 10 (NAT10) inhibitor. Improves nuclear shape in HGPS (Hutchinson-Gilford progeria syndrome) cells and lamin A/C depleted cells.
技术数据 for Remodelin
| 分子量 | 282.36 |
| 公式 | C15H14N4S |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 949912-58-7 |
| PubChem ID | 44442376 |
| InChI Key | XAEJIFARBQJLML-UHFFFAOYSA-N |
| Smiles | N#CC(C=C1)=CC=C1C2=CSC(N/N=C3CCCC/3)=N2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Remodelin
参考文献 for Remodelin
参考文献是支持产品生物活性的出版物。
Larrieu et al (2014) Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science 344 527 PMID: 24786082
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关键词: Remodelin, Remodelin supplier, NAT10, N-acetyltransferase, 10, aging, inhibitors, HGPS, Hutchinson-Gilford, progeria, syndrome, laminopathies, laminopathy, inhibits, Other, Transferases, 5193, Tocris Bioscience
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