Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewNIBR 189
说明： Potent and selective EBI2 (GPR183) receptor antagonist
化学名： (2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one
纯度： ≥99% (HPLC)
生物活性 for NIBR 189
NIBR 189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively). Exhibits selectivity for EBI2 over a panel of other receptors, enzymes and transporters. Blocks oxysterol-induced migration of U937 monocyte cells. Orally bioavailable.
技术数据 for NIBR 189
| 分子量 | 429.31 |
| 公式 | C21H21BrN2O3 |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 1599432-08-2 |
| PubChem ID | 36295259 |
| InChI Key | OFHXXBRBGWUOHR-NYYWCZLTSA-N |
| Smiles | BrC1=CC=C(/C=C/C(N2CCN(C(C3=CC=C(OC)C=C3)=O)CC2)=O)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for NIBR 189
参考文献 for NIBR 189
参考文献是支持产品生物活性的出版物。
Gessier et al (2014) Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor. J.Med.Chem. 57 3358 PMID: 24678947
按标靶查看相关产品
按产品操作查看相关产品
关键词: NIBR 189, NIBR 189 supplier, NIBR189, potent, selective, EBI2, GPR183, Epstein-bar, virus, induced, gene, 2, receptors, antagonists, orally, bioavailable, Orphan, 7-TM, Receptors, 5203, Tocris Bioscience
NIBR 189 的评论
目前没有该产品的评论。 Be the first to review NIBR 189 and earn rewards!
Have you used NIBR 189?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image