AC 55541

Name: AC 55541
Brand: Tocris Bioscience
SKU: 3369

Cat. No. 3369 6 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3369 has been discontinued.

View all Protease-Activated Receptors products.

说明： Potent and selective PAR₂ agonist

化学名： (2E)-2-[1-(3-Bromophenyl)ethylidene] α-(benzoylamino)-3,4-dihydro-4-oxo-1-phthalazineacetic acid hydrazide

纯度： ≥97% (HPLC)

说明书

引用文献 (6)

生物活性技术数据说明书参考文献

生物活性 for AC 55541

AC 55541 is a potent and selective protease-activated receptor 2 (PAR₂) agonist (pEC₅₀ = 6.7) that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. Stimulates cell proliferation, PI hydrolysis and Ca²⁺ mobilization in vitro (pEC₅₀ values are 6.7, 5.9 and 6.6 respectively) and exhibits pronociceptive activity in vivo.

技术数据 for AC 55541

分子量	518.36
公式	C₂₅H₂₀BrN₅O₃
储存	Store at -20°C
纯度	≥97% (HPLC)
CAS Number	916170-19-9
PubChem ID	9589606
InChI Key	UCUHFWIFSHROPY-RWPZCVJISA-N
Smiles	O=C2C1=CC=CC=C1C(C(NC(C3=CC=CC=C3)=O)C(N/N=C(C)/C4=CC=CC(Br)=C4)=O)=NN2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for AC 55541

分析证书/产品说明书

化学品安全技术说明书

参考文献 for AC 55541

参考文献是支持产品生物活性的出版物。

Seitzberg et al (2008) Discovery of potent and selective small-molecule PAR-2 agonists. J.Med.Chem. 51 5490 PMID: 18720984

Gardell et al (2008) Identification and characterization of novel small-molecule protease-activated receptor 2 agonists. J.Pharmacol.Exp.Ther. 327 799 PMID: 18768780

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关键词: AC 55541, AC 55541 supplier, Potent, selective, PAR2, agonists, Receptors, Protease-Activated, proteinase-activated, AC55541, 3369, Tocris Bioscience