Pharmacology
All Targets
7-TM Receptors
Ion Channels
Nuclear Receptors
Enzyme-Linked Receptors
Transporters
Enzymes
Other Pharmacology
Cellular Processes
Angiogenesis
Apoptosis
Cell Cycle
Cell Metabolism
Cytoskeleton & Motor Proteins
ECM & Adhesion Molecules
Signal Transduction
Stem Cells
Signaling Pathways 
Product Type
All Products
New Products
Small Molecules
Peptides
Controlled Substances
Toxins
Caged Compounds
Fluorescent Probes
Screening Libraries
Ligand Sets
Other Product Types
Research Area
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
Product Type
All Products
New Products
Small Molecules
Peptides
Controlled Substances
Toxins
Caged Compounds
Fluorescent Probes
Screening Libraries
Ligand Sets
Other Product Types
Research Area
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
Properties of Potassium Channels
| Type | Inward Rectifier | ATP-Sensitive | Voltage-Sensitive | Ca2+-Activated |
|---|
| Subtype | - | - | A-type | Delayed rectifier | Large conductance (maxi-K, BK) | Small conductance (SK) |
| Effect of Ca2+ | Insensitive | Insensitive | Insensitive | Insensitive | Variable | High sensitivity |
| Effect of Voltage | Strong, inward rectification | Weak, inward rectification | Sensitive | Sensitive | Sensitive | Insensitive |
| Effect of ATP | Insensitive | Inhibits channel opening | Insensitive | Insensitive | Insensitive | Insensitive |
| Conductance (pS) | 5-30 | 5-90 | < 1-20 | < 1-20 | 100-250 | 6-14 |
References
Robertson et al (1997) The real life of voltage-gated K+ channels: more than model behaviour. TiPS 18 474. Mathie et al (1998) Voltage-activated potassium channels in mammalian neurons and their block by novel pharmacological agents. Gen.Pharmacol. 30 13. Vergara et al (1998) Calcium-activated potassium channels. Curr.Opin.Neurobiol. 8 321.
.