Welcome to Tocris Bioscience
The leading supplier of high performance life science reagents
Tocris provides the highest performing and most innovative range of research reagents available. Our range of over 3,000 products consists of small molecules, peptides and antibodies and is a unique collection of novel and exclusive tools for laboratory research.
Featured Products
New for July
Axin stabilizer
3532 | endo-IWR 1
Inhibitor of Wnt signaling. Induces an increase in Axin2 protein levels; promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes.
Related Products: IWP 2 PNU 74654 XAV 939High affinity 5-HT1A receptor antagonist
3282 | NAD 299
Ki = 0.6 nM in vitro. Enhances the action of selective 5-HT reuptake inhibitors and reverses citalopram-induced inhibition of serotonergic cell firing.
Related Products: Xaliproden 8-Hydroxy-DPAT hydrobromide (S)-WAY 100135GSK-3β inhibitor
3835 | TWS 119
IC50 = 30 nM. Induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs).
Related Products: SB 216763 SB 415286 KenpaulloneSelective Rho-kinase (ROCK) inhibitor
3846 | Y 39983
IC50 values are 0.0036, 0.42 and 0.81 μM for ROCK, PKC and CaMKII respectively. Promotes neurite regeneration in vitro and induces axonal regeneration in vivo. Derived from Y-27632 (Cat. No. 1254).
Related Products: SR 3677 Y-27632 Glycyl-H 1152TRPV1 antagonist
3875 | BCTC
Inhibits acid- and capsaicin-induced activation of rat TRPV1 receptors (IC50 values are 6.0 and 35 nM respectively). Displays analgesic properties in rat models of inflammatory and neuropathic pain. CNS penetrant.
Related Products: Anandamide (in TocrisolveTM 100) Capsazepine 5'-IodoresiniferatoxinBuy Now / Print Quote
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Tocris Product News
Agreement to Supply Pfizer Research Compounds
Tocris announces an agreement with Pfizer which will result in a wide range of Pfizer compounds being made available to the global research community.
New Product Guide
Highlights over 250 new products added in 2009/10. Request a copy or view PDF today.