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Properties of Voltage-gated Calcium Channels
| Channel Type | L | T | N | P | Q | R |
|---|
| Conductance (pS) | 25 | 5-9 | ~ 20 | 9-19 | 16 | - |
| Activation Threshold | High | Low | High | High | High | High |
| Deactivation Rate | Fast | Slow | Fast | Fast | Fast | Fast |
| Inactivation Rate | Slow | Fast | Moderate | Very Slow | Moderate | Fast |
| Permeability | Ba2+ > Ca2+ | Ba2+ = Ca2+ | Ba2+ > Ca2+ | Ba2+ > Ca2+ | Ba2+ > Ca2+ | Ba2+ > Ca2+ |
References
Perez-Reyes and Schneider (1994) Calcium channels: structure, function, and classification. Drug Dev.Res. 33 295. Catterall (1995) Structure and function of voltage-gated ion channels. Ann.Rev.Biochem. 64 493.